Antimicrobial use regulations are associated with increased susceptibility among bovine Salmonella isolates from a U.S. surveillance system.

ABSTRACT: Health authorities around the world have called to limit antimicrobial use in food-producing animals. In the United States, two recent regulatory actions have changed the use of antimicrobials in livestock, banning production uses in 2017 and restricting extra-label use of cephalosporins in 2012. This study aimed to assess the impact of the 2012 and 2017 regulations on antimicrobial use in cattle in the United States by analyzing 18,627 bovine Salmonella AMR susceptibility patterns using data from the National Antimicrobial Resistance Monitoring System (NARMS). Logistic regression was used to model the odds of being a susceptible isolate. Additionally, interval-censored accelerated failure time (AFT) models were used to analyze changes in minimum inhibitory concentrations (MICs) ove

SUBMITTER: Cobo-Angel C 

PROVIDER: S-EPMC11848768 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature