Corallocarpus glomeruliflorus: Pharmacological potential revealed by phytochemical and in silico investigations.

ABSTRACT: Corallocarpus glomeruliflorus (CGP), a plant native to Yemen, has been traditionally used for the management of various health conditions, including cancer, inflammation, and diabetes. This study presents the first comprehensive phytochemical and pharmacological investigation of CGP, revealing novel molecular mechanisms and therapeutic potential. Phytochemical analysis of the CGP extract revealed the presence of diverse bioactive compounds, including phenols, flavonoids, and other secondary metabolites. Notably, this is the first report identifying maritimetin, assafoetidin, kaempferol 3-rhamnoside 7-xyloside, and lespenefril in CGP, compounds with significant therapeutic potential. The total phenolic content was 88.12 ± 4.48 mg GAE/g, significantly higher than previously reported f

SUBMITTER: Naji Bin-Asal FS 

PROVIDER: S-EPMC11848803 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature