Body mass index changes after fecal microbiota transplantation for recurrent Clostridioides difficile infection.

ABSTRACT:

Background

Fecal microbiota transplantation (FMT) is a successful therapy for Clostridioides difficile infection (CDI). FMT from overweight donors is speculated to influence the recipient's body mass index (BMI) after administration for CDI.

Objectives

We investigated changes in the recipient's BMI after FMT in relation to the donor's BMI.

Design

We conducted a retrospective cohort study involving patients who underwent FMT for recurrent CDI at Mayo Clinic between 2012 and 2019.

Methods

We analyzed demographic and donor data for patients undergoing FMT at Mayo Clinic (2012-2019). Recipient BMI (pre- and post-FMT) and donor BMI were extracted from medical records. Mixed-effects linear regression was used to evaluate the impact of donor BMI, donor BMI cate

SUBMITTER: Sehgal K 

PROVIDER: S-EPMC11848891 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature