Esophageal submucosal gland duct adenoma: a case report and literature review.

ABSTRACT:

Introduction

Esophageal submucosal gland duct adenoma (ESGDA) is a rare, benign tumor with non-specific clinical features and imaging findings, often leading to misdiagnosis.

Case report

In this report we describe the clinicopathological features of a new-onset case of ESGDA and review 19 previously-reported ESGDA cases in the literature.

Results

The median age of the 20 patients was 70 years, and the male-to-female ratio was 5:2. Lesions located in the lower esophagus accounted for 81% of the cases. Chest and abdominal discomfort were the main clinical symptoms, and endoscopic findings mostly included polypoid masses that were impossible to correctly diagnose prior to excision and biopsy. On microscopic examination, the submucosal tumor was found to be composed of gl

SUBMITTER: Zhou B 

PROVIDER: S-EPMC11848948 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature