Functional segregation of rostral and caudal hippocampus in associative memory.

ABSTRACT:

Introduction

The hippocampus plays a crucial role in episodic memory. Given its complexity, the hippocampus participates in multiple aspects of higher cognitive functions, among which are semantics-based encoding and retrieval. However, the "where," "when" and "how" of distinct aspects of memory processing in the hippocampus are still under debate.

Methods

Here, we employed a visual associative memory task that involved encoding three levels of subjective congruence to delineate the differential involvement of the rostral and caudal portions (also referred as anterior/posterior portions) of the human hippocampus during memory encoding, recognition and associative recall.

Results

Through stereo-EEG recordings in epilepsy patients we show that associative memory is refl

SUBMITTER: Vorobiova AN 

PROVIDER: S-EPMC11848949 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature