Contrasting the clinical and biological characteristics of young and old COPD patients.

ABSTRACT:

Background

The ECLIPSE study was a large, international, prospective, controlled, observational study that included COPD patients (Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades 2-4), as well as smoking and non-smoking participants with normal spirometry, aged 40-75 years, who were followed-up regularly for 3 years. Here we sought to contrast the clinical and biological characteristics of young COPD versus controls of similar age and older COPD patients included in ECLIPSE.

Methods

We compared 106 young (<50 years) and 488 old (>70 years) COPD patients, as well as 119 young smokers and 92 nonsmoker controls (<50 years) with normal spirometry.

Results

Young COPD patients: 1) were more symptomatic than young controls, often reported a family

SUBMITTER: Vila M 

PROVIDER: S-EPMC11849125 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature