Relationship between the geriatric nutritional risk index and sepsis in elderly critically ill patients: a retrospective cohort study.

ABSTRACT:

Objective

To investigate the relationship between the geriatric nutritional risk index (GNRI) and sepsis in elderly critically ill patients.

Methods

We extracted data from the MIMIC-IV database for patients aged 65 and older who were first-time admissions to the Intensive Care Unit. The GNRI, derived from serum albumin, height, and weight, served as the exposure variable. The main outcome was the occurrence of sepsis. We utilized multivariable logistic regression to evaluate the association between GNRI and sepsis. Additionally, we employed restricted cubic splines to evaluate the potential nonlinear relationship between GNRI and the incidence of sepsis.

Results

The study included 3,535 elderly patients, with 2,005 (56.7%) developing sepsis. Septic patients had signif

SUBMITTER: Jin Y 

PROVIDER: S-EPMC11849206 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature