Development and validation of the systemic nutrition/inflammation index for improving perioperative management of non-small cell lung cancer.

ABSTRACT:

Background

Systemic nutrition and inflammation status is recognized for its influence on cancer survival, yet its role in perioperative outcomes remains poorly defined. This study aimed to refine the assessment of systemic nutrition and inflammation status in non-small cell lung cancer (NSCLC) patients and to elucidate its impact on perioperative outcomes.

Methods

All patients underwent video-assisted thoracoscopic lobectomy, with their nutrition and inflammation status assessed based on preoperative blood tests. The development cohort, comprising 1497 NSCLC patients from two centers, evaluated the predictive value of systemic nutrition/inflammation indicators for perioperative endpoints and formulated the systemic nutrition-inflammation index (SNII). The tertiles of SNII we

SUBMITTER: Wang P 

PROVIDER: S-EPMC11849302 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature