Surface imprinted microhelical magnetic polymer nanocomposite fibers for targeted lysozyme separation.

ABSTRACT: Magnetic microhelical structures have recently drawn attention as microswimmers capable of mimicking bacterial propulsion in the low Reynolds number regime. Such structures can be used in microfluidic bioseparation or targeted delivery and their interaction with proteins is extremely important. In this study we fabricated silica coated magnetic microhelices resembling artificial bacterial flagella like structures via electrospinning magnetite nanoparticle incorporated polystyrene nanocomposite solution followed by silica sol coating. Two model proteins, Lysozyme (Lyz) and Bovine Serum Albumin (BSA), were used for protein imprinting along with a polydopamine layer on the magnetic microhelical substrates. The adsorption mechanism of lysozyme on the molecularly imprinted support system

SUBMITTER: Mohan A 

PROVIDER: S-EPMC11849538 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature