Increased Afterload in Patients With Acute Reduction in Left Ventricular Ejection Fraction Following Mitral Valve Transcatheter Edge-to-Edge Repair.

ABSTRACT:

Aim

The mechanisms and clinical importance of acute reduction (ARD) in left ventricular (LV) function following transcatheter edge-to-edge repair (TEER) for mitral regurgitation (MR) remains unclear. This study aimed to non-invasively evaluate the cardio-mechanical parameters, including end-systolic elastance (Ees) and arterial elastance (Ea), to explore their association with ARD following mitral TEER.

Methods and results

We performed a retrospective analysis of serial transthoracic echocardiography (TTE) studies before and after mitral TEER. Cardio-mechanical parameters were evaluated non-invasively using a modified single-beat method. After the exclusion of nine patients requiring intravenous catecholamine infusion, the study cohort comprised 49 consecutive patients (25 m

SUBMITTER: Hashimoto K 

PROVIDER: S-EPMC11849581 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature