Illicit drug use derived from wastewater-based epidemiology in Iran, their removal during wastewater treatment, and occurrence in receiving waters.

ABSTRACT: This study aimed to measure the licit and illicit drug concentrations in wastewater treatment plants (WWTPs), their removal efficiency, and their consumption rate by wastewater-based epidemiology (WBE) approach. A 2-season monitoring program was undertaken for the first time in Iran. Residues of licit and illicit drugs (amphetamine, 3,4-methylenedioxyamphetamine, methamphetamine, codeine, 3,4-methylenedioxymethamphetamine, heroin, cocaine, and methadone) and major metabolites (benzoylecgonine, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and 6-monoacetylmorphine) were analyzed by LC-MS/MS in composite sampling after solid phase extraction method. These analytes were also measured in rivers vicinity to selected cities. The detected concentration in raw wastewater was converted into the

SUBMITTER: Asadi A 

PROVIDER: S-EPMC11849611 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature