Dose-volume parameter evaluation of a sub-fractionation workflow for adaptive radiotherapy of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system.

ABSTRACT:

Background and purpose

This study focuses on evaluating a sub-fractionation workflow for intrafraction motion mitigation of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system.

Materials and methods

The investigated workflow consisted of two sub-fractions where intrafraction drift correction steps were applied based on a daily reference plan. However, the daily contours were only rigidly shifted to match the intrafraction anatomies and therefore the clinical dosimetric constraints might be violated. In this work, daily contours were deformed to match the intrafraction anatomies and the online plans were re-calculated for a total of 15 patients. The deformed prostate contours were inspected by radiation oncologists and corrections were performed

SUBMITTER: Tsekas G 

PROVIDER: S-EPMC11849637 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature