Early and Late Complications Associated with Penile Cancer Surgery and the Impact of Human Papillomavirus Status: Findings from a Retrospective Norwegian Cohort Study.

ABSTRACT:

Background and objective

Penile cancer (PeCa) and penile intraepithelial neoplasia (PeIN) are rare diseases, and the burden of complications associated with surgery remains under-reported. The objective was to evaluate the early (≤30 d) and late (>30 d) complications and the impact of human papillomavirus (HPV) status.

Methods

A retrospective analysis was conducted of a cohort consisting of 201 consecutive and treatment-naïve patients with PeCa/PeIN undergoing surgery (penile sparing, and partial and total amputation) between January 1, 2000 and December 31, 2023 at a tertiary centre as part of a centralised regional service.

Key findings and limitations

The median follow-up time was 39 (interquartile range 21, 76) mo. The early and late patient complication rates wer

SUBMITTER: Juliebo-Jones P 

PROVIDER: S-EPMC11849643 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature