Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis.

ABSTRACT:

Background

Rheumatoid arthritis (RA) is known as an inflammatory illness. Evidence shows that Vitamin D modulates immunologic function and inflammation by affecting various immunological cells. We decided to run a systematic review and meta-analysis to investigate the relationship between vitamin D supplementation and the outcomes of adult patients suffering from RA.

Methods

We searched electronic databases, using specific search terms in PubMed, Scopus, and ISI Web of Science, until May 2024. Clinical studies involving patients with RA were included if they compared the effects of vitamin D supplementation to either a placebo or standard care. The results from the selected studies were presented as weighted mean differences (WMD) along with a 95 % confidence interval (CI).<

SUBMITTER: Ranjbar M 

PROVIDER: S-EPMC11849653 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature