Continued T12 transmission and shared antibiotic resistance during 2018-2023 Vibrio cholerae outbreaks in Cameroon.

ABSTRACT: Seventh pandemic Vibrio cholerae was first identified in Cameroon in 1971, causing several sporadic disease clusters with few cases. More recent years have seen larger cholera outbreaks, but the mechanism behind these periodic outbreaks is poorly understood, and it is unclear the degree to which antibiotic resistant strains contribute to disease burden and spread. We used whole genome sequencing to characterize 13 V. cholerae isolates from the 2018-2019, 2020, and 2021-2023 cholera epidemics in Cameroon. All these isolates belonged to the T12 lineage, and most showed the same antimicrobial resistance (AMR) pattern regardless of year. This suggests that cholera outbreaks in Cameroon are, at least in part, a continuation of the outbreaks previously reported in 2018 and as far back as 2012. T

SUBMITTER: Ngomtcho SCH 

PROVIDER: S-EPMC11849833 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature