Association between neutrophile-to-lymphocyte ratio and risk of deep vein thrombosis in patient receiving lower extremity orthopedic surgery: A meta-analysis.

ABSTRACT:

Objective

This meta-analysis aimed to quantitatively synthesize evidence on the association between the preoperative neutrophil-to-lymphocyte ratio (NLR) and the risk of deep vein thrombosis (DVT) in patients undergoing lower extremity orthopedic surgery.

Methods

Medline, Embase, Google Scholar, and the Cochrane Library were systematically searched for observational studies that examined the relationship between preoperative NLR and DVT risk in patients undergoing lower extremity procedures. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effects models.

Results

Ten studies involving 5,697 patients were included in the meta-analysis. The pooled incidence of DVT across the studies was 13.8% (95% CI: 9.7%-19.2%). Elevated NLR wa

SUBMITTER: Chen IW 

PROVIDER: S-EPMC11849845 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature