Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery.

ABSTRACT:

Background

Obesity is a growing health concern worldwide, including United Arab Emirates. Bariatric surgery is an effective treatment option, with to date unclear weight loss mechanisms. In this prospective study, we explored post-bariatric surgery changes in energy homeostasis, gut peptides, hormones, and gut microbiota.

Method

We recruited 19 Emirati adults who were planning to undergo sleeve gastrectomy (SG). We assessed the energy requirements using 24-hour diet recalls, indirect calorimetry for resting energy expenditure (REE), and a questionnaire for appetite. Anthropometrics included body mass index (BMI), waist circumference, waist-to-height ratio, fat mass, fat-free mass, and percentage of body fat. Gut peptides, including peptide YY (PYY), glucagon-like peptide-1/2

SUBMITTER: Ali Ahmad M 

PROVIDER: S-EPMC11849869 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature