Survival analysis between different treatment strategies of mixed adenoneuroendocrine carcinoma (MANEC): a population-based study.

ABSTRACT:

Background

Mixed adenoneuroendocrine carcinoma (MANEC) is rare and heterogeneous. Currently, there is no concise treatment standard for MANEC. This study aimed to explore the prognostic impact of different treatment methods in MANEC.

Methods

The surveillance, epidemiology and end results database was utilized to evaluate the outcomes of MANEC using propensity score matching (PSM) , stratified and site-specific survival analysis.

Results

A total of 935 patients diagnosed with MANEC were enrolled in this study. Across most analyses, surgery performance (compared with no surgery) was associated with improved survival outcomes for MANEC patients, except for the site-specific analysis of small intestine, in which no significant association between surgery and patients' sur

SUBMITTER: Li W 

PROVIDER: S-EPMC11850044 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature