Association between adult body shape index and serum levels of the anti-aging protein Klotho in adults: a population-based cross-sectional study of the NHANES from 2007 to 2016.

ABSTRACT:

Purpose

Adult body shape index (ABSI) is widely recognized as a reliable indicator for evaluating body fat distribution and dysfunction. However, the relationship between ABSI and Klotho protein, known for its anti-aging biological function, has not yet been investigated. Therefore, the aim of this study was to assess the correlation between ABSI and serum Klotho levels in adults residing in the United States.

Methods

A cross-sectional study of participants was conducted based on the 2007-2016 National Health and Nutrition Examination Survey. Visceral adiposity was determined using the ABSI score, and Klotho protein concentration was measured using an enzyme-linked immunosorbent assay kit. Multiple regression models were used to estimate the association between ABSI and Klot

SUBMITTER: Gong L 

PROVIDER: S-EPMC11850266 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature