Effects of long-term indoor air purification intervention on cardiovascular health in elderly: a parallel, double-blinded randomized controlled trial in Hong Kong.

ABSTRACT: Ambient fine particulate matter (PM_2.5) is a leading environmental risk factor globally, and over half of the associated disease burden are caused by cardiovascular disease. Numerous randomized controlled trials (RCT) have investigated the short-term cardiovascular benefits of indoor air purifiers (IAPs), but major knowledge gaps remain on their longer-term benefits. In this 1-year, randomized, double-blinded, parallel controlled trial of 47 elderly (n_{true-purification} = 24; n_{sham-purification} = 23) aged ≥70 years, true-purification reduced household PM_2.5 levels by 28% and maintained lower exposure throughout the year compared to the sham-purification group. After 12 months of intervention, a significant reduction of diastolic blood pressure was

SUBMITTER: Xia X 

PROVIDER: S-EPMC11850294 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature