Within- and between-day test-retest reliability of responses to rapid bilateral anterolateral magnetic phrenic nerve stimulation in healthy humans (ReStim).

ABSTRACT:

Background

Mechanical ventilation can lead to lung injury and diaphragmatic dysfunction. Rapid bilateral anterolateral magnetic phrenic nerve stimulation (rBAMPS) may attenuate both of the aforementioned issues by inducing diaphragm activation. However, in order for rBAMPS to become part of standard of care, the reliability of inspiratory responses to rBAMPS needs to be established.

Methods

Eighteen healthy participants (9F) underwent five blocks of 1-s rBAMPS at 25 Hz starting at 20% of maximal stimulator output with 10% increments. Three blocks were completed on the same day to test within-day reliability, and two additional blocks were each completed on subsequent days to test between-day reliability. Mean transdiaphragmatic pressure (P_di,mean), tidal volume (V

SUBMITTER: Boyle KGPJM 

PROVIDER: S-EPMC11850319 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature