Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis.

ABSTRACT:

Objective

This study aimed to investigate the association between blood manganese and selenium levels and hepatic steatosis among adolescents, using data from the National Health and Nutrition Examination Survey (NHANES) 2017-2023.

Methods

A cross-sectional analysis was conducted using data from 2,459 adolescents (aged 12-19 years) with complete data on liver ultrasound transient elastography, blood manganese, and selenium levels. Hepatic steatosis was defined as a controlled attenuation parameter (CAP) score of ≥248 dB/m, a measure of liver steatosis, which is a primary characteristic and a less severe stage of hepatic steatosis, assessed by vibration-controlled transient elastography (VCTE). Multivariate logistic regression models were used to assess the associations betwe

SUBMITTER: You B 

PROVIDER: S-EPMC11850372 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature