The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.

ABSTRACT:

Purpose

Imbalance between Th1 and Th2 cells correlated with increased disease incidence, is well-documented in the older adult. Both acute and chronic exercise induce a transient shift in organic homeostasis, modulating the immune system and impacting the balance between Th1 and Th2 cells. This review investigates the impact of acute and chronic exercise on immune markers of Th1 and Th2 cells in the older adults.

Methods

This study was conducted as a systematic review, following PRISMA guidelines, databases including PubMed, Web of Science, Embase, Science Direct, and Scopus were searched until March 2024, identifying randomized controlled trials and prospective observational studies that examined the effects of acute and chronic exercise on intracellular and surface markers

SUBMITTER: Teodoro TH 

PROVIDER: S-EPMC11850391 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature