Association of baseline plasma fibrinogen levels with cognitive and affective status at 30 and 90 days in individuals with ischemic stroke: A prospective study from Nigeria.

ABSTRACT:

Background

The influence of fibrinogen as a risk factor in developing poststroke neuropsychological and cognitive problems is underreported. This study aimed to evaluate the relationship between baseline fibrinogen levels and depression, anxiety, and cognition 30- and 90-day after stroke.

Methods

This prospective study involved 48 patients with first-ever mild-to-moderate ischemic stroke, whose plasma fibrinogen levels were assessed within 24 h of stroke onset. Clinical depression, anxiety, and cognitive impairment were evaluated by the Hospital Anxiety and Depression Scale and Montreal Cognitive Assessment at 30- and 90-day after stroke.

Results

After adjusting for important covariates, the multiple linear regression models showed that baseline plasma fibrinogen was

SUBMITTER: Ademoyegun AB 

PROVIDER: S-EPMC11850936 | biostudies-literature | 2024 Oct-Dec

REPOSITORIES: biostudies-literature