Missense Mutations in FDNC5 Associated with Morphometric Traits and Meat Quality in Hainan Black Goats.

ABSTRACT: Goats are widely recognized for their adaptability and resource efficiency, making them an excellent choice for sustainable farming. However, the Hainan Black goat (HNBG), a vital breed in southern China's tropical regions, faces significant challenges that threaten its productivity and economic viability. Specifically, young HNBGs exhibit stunted growth and poor muscle development, indicating the breed may have more genetic defects that cause the poor phenotypes. The FNDC5 gene, which encodes the protein irisin, plays a key role in promoting mitochondrial biogenesis and oxidative metabolism by activating critical signaling molecules such as PGC-1α, thereby enhancing muscle endurance and metabolic efficiency. This study aimed to investigate the impact of missense mutations in the

SUBMITTER: Huang J 

PROVIDER: S-EPMC11851529 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature