Antimicrobial, Anti-Biofilm, Anti-Quorum Sensing and Cytotoxic Activities of Thymbra spicata L. subsp. spicata Essential Oils.

ABSTRACT: Background/Objectives: Essential oils of Thymbra spicata subsp. spicata are known for their rich phytochemical content and bioactive properties. This study aimed to evaluate the antimicrobial, anti-biofilm and anti-quorum sensing, as well as the cytotoxic activities of T. spicata subsp. spicata essential oils (TS-EO1 and TS-EO2) obtained from two different localities in Türkiye, along with a detailed chemical composition analysis. Methods: TS-EO1 and TS-EO2 were obtained by the hydrodistillation method and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS) to determine their phytochemical profiles. Antimicrobial activities were assessed against Gram-positive and Gram-negative bacteria, and fungal strains were assessed using the broth micro

SUBMITTER: Barak TH 

PROVIDER: S-EPMC11851892 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature