Unveiling the Potential of Three Endemic Gypsophila L. (Caryophyllaceae) Taxa as Promising Carbonic Anhydrase Inhibitors-Bio-Metabolic Profiles and In Vitro Evaluation of Enzyme Inhibition and Antioxidant Capacity.

ABSTRACT: The Caryophyllaceae family, commonly utilized in traditional medicine, exhibits various effects revealed by ethnopharmacological studies. Thus, the diuretic effect of the leaf and stem of three Gypsophila taxa endemic to Türkiye was evaluated for the first time by comparing their bio-metabolic profiles, antioxidant capacities, carbonic anhydrase inhibition, and infrared spectra. The leaf and stem of Gypsophila taxa were macerated in 50% ethanol and 50% water, bio-metabolic profiles were performed by a new validated ultra-performance liquid chromatographic (UPLC) method and spectrophotometric methods, the antioxidant capacity was determined by DPPH and ABTS assays, and the in vitro diuretic activity was evaluated by carbonic anhydrase inhibition. The results show that the G

SUBMITTER: Buker E 

PROVIDER: S-EPMC11852014 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature