Integrated Transcriptome and Targeted Metabolome for Resolving Flavonoid Biosynthesis in Figs (Ficus carica Linn.).

ABSTRACT: Figs are an edible and medicinal plant rich in polyphenols and flavonoids with unique pharmacological effects. However, the mechanism of flavonoid synthesis in figs is not clear. In this study, fig fruits of six varieties were collected for RNA sequencing and UPLC-MS data collection. The results showed that a total of 39 differential metabolites were identified by targeted metabolomics, and their contents were determined by UPLC-MS. The clustered heat map analysis showed that most of the differential metabolites were highly accumulated in BRD and FY. A total of 62 flavonoid biosynthesis pathway genes were identified by transcriptome analysis, and FcCHS, FcCHI, FcFLS, FcCYP, and FcDFR were the key genes identified for the accumulation of flavonoids and fla

SUBMITTER: Sun J 

PROVIDER: S-EPMC11852052 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature