Age-based host response to Turkey arthritis reovirus in commercial Turkeys in the presence of maternally derived antibodies.

ABSTRACT:

Background

Turkey arthritis reovirus (TARV) causes arthritic lameness in market-age turkeys. Since 2011, highly pathogenic TARV strains have caused significant economic losses in the turkey industry due to increased culling, reduced market weights, and decreased carcass quality, necessitating more effective control measures. Autogenous vaccine prevention strategies have been inefficacious partly due to a limited understanding of age-related susceptibility of turkeys to TARV. This study investigated age-related host and gut microbiota responses to TARV infection in commercial turkeys derived from vaccinated breeder hens. Poults with known maternally derived antibody titers were orally challenged with TARV O'Neil strain at 1-, 3-, and 7- weeks of age (WOA) and monitored for cloacal v

SUBMITTER: Khatiwada S 

PROVIDER: S-EPMC11852562 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature