Expanding the Applicability of Electroactive Polymers for Tissue Engineering Through Surface Biofunctionalization.

ABSTRACT: Polyvinylidene fluoride (PVDF) is a synthetic semicrystalline fluoropolymer with great potential for tissue engineering applications. In addition to its excellent mechanical strength, thermal stability, biocompatibility and simple processability into different morphologies, the relevance of PVDF-based materials for tissue engineering applications comes for its electroactive properties, which include piezo-, pyro- and ferroelectricity. Nevertheless, its synthetic nature and inherent hydrophobicity strongly limit the applicability of this polymer for certain purposes, particularly those involving cell attachment. In addition, the variable adhesion of cells and proteins to PVDF surfaces with different net surface charge makes it difficult to accurately compare the biological response in each

SUBMITTER: Leiva B 

PROVIDER: S-EPMC11852601 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature