The Impact of the COVID-19 Pandemic on the Antibiotic Resistance of Gram-Negative Pathogens Causing Bloodstream Infections in an Intensive Care Unit.

ABSTRACT: Background/Objectives: In this research, we aimed to analyze the trend of the antimicrobial resistance pattern of Gram-negative isolated in blood samples collected from patients with severe invasive infections hospitalized in the intensive care unit in selected periods during and after COVID-19. Methods: A retrospective study of bacterial pathogens was performed on 481 patients admitted to the ICU between 2020 and 2023. The resistance patterns were analyzed using the Vitek 2 Compact system. Results. A total of 686 Gram-negative bacterial isolates were obtained. The most frequently detected Gram-negative pathogens were Klebsiella spp. (30.91%), Acinetobacter spp. (24.64%), and Escherichia coli (18.95%). Almost 50% of all the pathogens were multidrug

SUBMITTER: Golli AL 

PROVIDER: S-EPMC11852776 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature