The association of selenium exposure with the odds of metabolic syndrome: a dose-response meta-analysis.

ABSTRACT:

Background

Selenium is a key regulator of metabolic homeostasis. It has been proposed that exposure to selenium might be associated with metabolic syndrome (MetS). However, the results are contradictory. This meta-analysis was carried out to analyze the relationships between selenium levels in biological samples and odds of Mets.

Methods

We searched Scopus and PubMed databases up until September 2024 to identify relevant studies. Odds ratio (OR) and 95% confidence interval was used to pool the data using a random effects model.

Results

The meta-analysis encompassed 18 observational studies involving 21,481 participants. It found that higher selenium exposure was related to an elevated likelihood of MetS (OR = 1.30, 95% CI = 1.12-1.51), even after controlling for covar

SUBMITTER: Yuan R 

PROVIDER: S-EPMC11853193 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature