A Compact Fluorescence System for Tumor Detection: Performance and Integration Potential.

ABSTRACT: Fluorescence-guided surgery (FGS) is an innovative technique for accurately localizing tumors during surgery, particularly valuable in brain tumor detection. FGS uses advanced spectral and imaging tools to provide precise, quantitative fluorescence measurements that enhance surgical accuracy. However, the current challenge with these advanced tools lies in their lack of miniaturization, which limits their practicality in complex surgical environments. In this study, we present a miniaturized fluorescence detection system, developed using state-of-the-art CMOS color sensors, to overcome this challenge and improve brain tumor localization. Our 3.1 × 3 mm multispectral sensor platform measures fluorescence intensity ratios at 635 nm and 514 nm, producing a high-resolution fluorescence distrib

SUBMITTER: Ndabakuranye JP 

PROVIDER: S-EPMC11853339 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature