Is the Sentinel Lymph Node Biopsy Safe and Accurate After Previous Surgery for Vulvar Squamous Cell Carcinoma? A Systematic Review.

ABSTRACT: Lymphadenectomy for vulvar carcinoma is characterized by many complications. Studies have demonstrated the diagnostic accuracy of sentinel lymph node biopsy (SLNB) as a valid alternative to lymphadenectomy in the early stages of vulvar squamous cell carcinoma (VSCC). Objective: To evaluate the feasibility, safety, and accuracy, as well as the oncological outcomes of SLNB following scar injection; in addition, to assess the role of a repeat sentinel node procedure in patients with local vulvar recurrence after primary treatment. Materials and Methods: A systematic computerized search of the literature was performed in the main electronic databases (MEDLINE, EMBASE, Web of Science, Pub Med, and Cochrane Library) from 2010 to August 2024. Only scientific publications in English

SUBMITTER: Della Corte L 

PROVIDER: S-EPMC11853356 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature