Honey, Gellan Gum, and Hyaluronic Acid as Therapeutic Approaches for Skin Regeneration.

ABSTRACT: Background/Objectives: Chronic wounds pose a significant health concern, with their prevalence increasing due to various etiologies. The global aging population further contributes to this rise, placing a substantial burden on healthcare systems in developed countries. This work aimed to develop new therapeutic options in the form of creams and dressings based on honey, gellan gum, and hyaluronic acid for preventing and treating chronic wounds across all stages. Methods: To address this, after the formulations were developed, in vitro cytocompatibility was determined. To confirm biocompatibility, an ovine wound model was used: full-thickness excisional wounds were treated with three formulations, namely gellan gum and honey sponges (GG-HNY), gellan gum, honey and hyaluronic a

SUBMITTER: Sousa P 

PROVIDER: S-EPMC11853393 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature