Exploring EEG resting state differences in autism: sparse findings from a large cohort.

ABSTRACT:

Background

Autism is a complex neurodevelopmental condition, the precise neurobiological underpinnings of which remain elusive. Here, we focus on group differences in resting state EEG (rsEEG). Although many previous reports have pointed to differences between autistic and neurotypical participants in rsEEG, results have failed to replicate, sample sizes have typically been small, and only a small number of variables are reported in each study.

Methods

Here, we combined five datasets to create a large sample of autistic and neurotypical individuals (n = 776) and extracted 726 variables from each participant's data. We computed effect sizes and split-half replication rate for group differences between autistic and neurotypical individuals for each EEG variable while accountin

SUBMITTER: Dede AJO 

PROVIDER: S-EPMC11853566 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature