Causal relationship of sleep duration on risks for metabolic syndrome: a Mendelian randomization study.

ABSTRACT:

Background

The cluster of cardiovascular risk factors, referred to as metabolic syndrome (MetS), represents a substantial risk factor for cardiovascular diseases and presents a significant public health challenge. However, previous epidemiological investigations exploring the link between sleep duration and MetS lack experimental evidence to establish a causal relationship. Hence, he objective of this study is to examine the association between sleep duration and MetS by employing the Mendelian randomization (MR) approach.

Methods

A cross-sectional study was conducted utilizing the Taiwan Biobank database, which comprised 33,270 predominantly Han Chinese individuals aged 30-70 years with no history of cancer and enrolled between 2008 and 2020. This study was conducted using

SUBMITTER: Lin CC 

PROVIDER: S-EPMC11853572 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature