Amiodarone use and prolonged mechanical ventilation after cardiac surgery: a single-center analysis.

ABSTRACT:

Background

Prolonged mechanical ventilation (PMV) after cardiac surgery increases the risk of complications such as pulmonary atelectasis and ventilator-associated pneumonia. This study aims to investigate the risk factors associated with delayed extubation, including the impact of cardiovascular medication.

Method

This retrospective, single-center study analyzed 1,976 patients who underwent open heart surgery at Nanjing Drum Tower Hospital from October 2020 to January 2023. Patients were categorized into early extubation (n = 1071) and delayed extubation (n = 905) groups. Multivariate logistic regression was employed to identify risk factors for delayed extubation. Amiodarone were indicated to be associated with delayed extubation. To further address bias, we derived a prop

SUBMITTER: Li X 

PROVIDER: S-EPMC11853816 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature