Associations between body composition, metabolic mediators and osteoarthritis in cats.

ABSTRACT:

Background

Osteoarthritis (OA) is a common, age-related joint disease in cats. The common finding of bilateral symmetric joint involvement may suggest influence from systemic factors, and could imply that body parameters such as excess body fat and cat size are important for OA development. We aimed to investigate associations between body composition and whole-body OA scores in 72 cats, using whole-body computed tomography (CT), and if serum concentrations of the metabolic mediators leptin, adiponectin and insulin-like growth factor-1 (IGF-1) reflected the total OA load. In addition, associations between body composition and metabolic mediators were determined. For data analyses, cats were grouped as smaller or larger according to the median value of the total body bone volume (bo

SUBMITTER: Ley CJ 

PROVIDER: S-EPMC11853884 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature