Metabolic outcomes in non-alcoholic and alcoholic steatotic liver disease among Korean and American adults.

ABSTRACT:

Background

This study investigated the prevalence and causal relationships of chronic metabolic diseases (diabetes, hypertension, and dyslipidemia) with steatotic liver disease (SLD), specifically metabolically associated alcoholic liver disease (MetALD).

Methods

We conducted a comprehensive analysis using cross-sectional data from the KNHANES from 2011 to 2021 and the NHANES from 1999 to 2020. Longitudinal data from 2001 to 2014 from the KoGES were used. Participants were categorized into the metabolic dysfunction-associated SLD(MASLD), MetALD, and ALD groups based on their hepatic steatosis index (HSI), including liver profiles, body composition, and diabetes, and alcohol consumption. Multivariable, including age and smoking status, logistic and Cox regression analyses wer

SUBMITTER: Kim Y 

PROVIDER: S-EPMC11853905 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature