CyberKnife in Pediatric Oncology: A Narrative Review of Treatment Approaches and Outcomes.

ABSTRACT: Pediatric cancers, while rare, pose unique challenges due to the heightened sensitivity of developing tissues and the increased risk of long-term radiation-induced effects. Radiotherapy (RT) is a cornerstone in pediatric oncology, but its application is limited by concerns about toxicity, particularly secondary malignancies, growth abnormalities, and cognitive deficits. CyberKnife (CK), an advanced robotic radiosurgery system, has emerged as a promising alternative due to its precision, non-invasiveness, and ability to deliver hypofractionated, high-dose RT while sparing healthy tissues. This narrative review explores the existing evidence on CK application in pediatric patients, synthesizing data from case reports, small series, and larger cohort studies. All the studies analyzed reported

SUBMITTER: Donati CM 

PROVIDER: S-EPMC11854067 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature