Determination and Comparison of the Pathogen Spectrum Evaluated by Microbial Culture and Multiplex PCR During Bronchoscopy with Regard to Clinical Utility of Routine Bronchial Wash in Patients with Various Pulmonary Diseases.

ABSTRACT: Background/Objectives: Bronchial wash for microbiological cultivation and/or multiplex polymerase chain reaction (PCR) is often routinely performed during bronchoscopy independent of the indication for bronchoscopy. This study aimed to determine and compare the pathogen spectrum evaluated by culture and PCR in bronchial secretion samples with regard to the underlying lung pathology. Methods: In this retrospective analysis, microbiological results from bronchial washes performed from February 2022 to September 2022 were collected in 245 patients (48.2% male, mean age 63.0 ± 13.9 years). Samples were assessed for bacteria/fungi culture and reported depending on the underlying pathology. Additional PCR was performed in 216 patients and compared to the results of the culture.

SUBMITTER: Milacek C 

PROVIDER: S-EPMC11854491 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature