Evaluating Rabies Test Accuracy: A Systematic Review and Meta-Analysis of Human and Canine Diagnostic Methods.

ABSTRACT: Background/Objectives: Rabies is almost invariably fatal once clinical symptoms manifest. Timely and accurate diagnosis is essential for effective treatment and prevention. Dogs are the principal reservoirs of the virus, particularly in developing nations, highlighting the importance of precise diagnostic and control measures to prevent human cases. This systematic review and meta-analysis assessed the accuracy of laboratory tests for diagnosing rabies in humans and dogs. Methods: The PubMed database was searched for published studies on rabies diagnosis between 1990 and 2024. Following PRISMA statement recommendations, we included 60 studies that met the selection criteria. Results: The results demonstrated the effectiveness of immunological tests like the Enzyme-Link

SUBMITTER: Candia-Puma MA 

PROVIDER: S-EPMC11854560 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature