The Predictive Role of Baseline ¹⁸F-FDG PET/CT Radiomics in Follicular Lymphoma on Watchful Waiting: A Preliminary Study.

ABSTRACT: Background: Patients with low tumour burden follicular lymphoma (FL) are managed with an initial watchful waiting (WW) approach. The way to better predict the time-to-treatment (TTT) is still under investigation for its possible clinical impact. This study explored whether radiomic features extracted from baseline ¹⁸F-FDG PET/CT could predict TTT in FL patients on WW. Methods: Thirty-eight patients on initial WW (grade 1-3a) were retrospectively included from 2010 to 2019. Eighty-one PET/CT morphological and first-level intensity radiomic features were extracted from the total metabolic tumour burden (TMTV), the lesion having the highest SUVmax and a reference volume-of-interest placed on the healthy liver. Models using linear regression (LR) and support vector mac

SUBMITTER: Maccora D 

PROVIDER: S-EPMC11854662 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature