Innovative Processing and Sterilization Techniques to Unlock the Potential of Silk Sericin for Biomedical Applications.

ABSTRACT: Silk sericin (SS), a by-product of the textile industry, has gained significant attention for its biomedical potential due to its biocompatibility and regenerative potential. However, the literature lacks information on SS processing methods and the resulting physicochemical properties. This study represents the first step in protocol optimization and standardization. In the present work, different processing techniques were studied and compared on SS extracted from boiling water: evaporation, rotary evaporation, lyophilization, and dialysis, which presented a recovery yield of approximately 27-32%. The goal was to find the most promising process to concentrate extracted SS solutions, and to ensure that the SS structure was highly preserved. As a result, a new cryo-lyophilization methodolo

SUBMITTER: Veiga A 

PROVIDER: S-EPMC11854797 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature