Colonic Manometry in Pediatric Patients with Spina Bifida: Results from a Retrospective Cohort Study.

ABSTRACT:

Background/objectives

Patients with spina bifida (SB) commonly experience neurogenic bowel dysfunction, characterized by defecation-related symptoms. While anorectal dysfunction and slow transit constipation (STC) have been implicated, the role of colonic motility in SB remains unclear. This study aimed to evaluate colonic motility in SB patients with refractory bowel dysfunction.

Methods

This retrospective cohort study included SB patients who failed the repeated optimization of a bowel regimen including stimulant laxatives and subsequently underwent anorectal manometry (ARM), colonic transit time (CTT) studies, or colonic manometry (CM). Diagnostic findings were analyzed alongside treatment outcomes.

Results

A total of 13 patients with myelomeningocele were included

SUBMITTER: Shan AYC 

PROVIDER: S-EPMC11854801 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature