FOXP2 Expression and Oral Feeding Success in Preterm Infants: Sex 2 Differences.

ABSTRACT:

Background

The FOXP2 gene, crucial for speech and motor functions, exhibits sex-specific expression differences. In premature infants, elevated FOXP2 expression, particularly in females, correlates with improved oral feeding readiness, indicating the potential for enhancing neonatal care.

Objective

This study investigates FOXP2 gene expression in premature newborns across five feeding stages using salivary RNA, focusing on sex differences and their impact on oral feeding readiness to refine neonatal clinical protocols.

Methods

FOXP2 expression was analyzed using RT-qPCR and the ΔΔCt method across five feeding stages in 45 premature newborns using saliva-derived RNA (n = 225).

Results

FOXP2 expression increased significa

SUBMITTER: Gomes LHF 

PROVIDER: S-EPMC11855131 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature