Association of BMP15 and GDF9 Gene Polymorphisms with Litter Size in Hu Sheep.

ABSTRACT: (1) Background: Litter size is one of the most important economic traits of sheep. The FecB locus has been extensively studied due to its significant impact on litter size in Hu sheep, and BMP15 and GDF9 have also been reported as major genes associated with litter size in sheep. This study aimed to identify variants of BMP15 and GDF9 and perform an association analysis of these variants with litter size in the Hu sheep breed. (2) Methods: In this study, exons of the BMP15 and GDF9 genes were fully sequenced to identify polymorphisms in Hu sheep. Population genetic parameters and haplotype frequencies were estimated, and an association analysis between these polymorphic loci and litter size was performed. Additionally, the protein structures

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11855564 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature