Identification and Expression Patterns of Critical Genes Related to Coat Color in Cashmere Goats.

ABSTRACT: Background/Objectives: Research on cashmere goat coat color is crucial for optimizing cashmere goat breeds and increasing their economic value. To identify key genes associated with the formation of cashmere goat coat color and to provide molecular markers for breeding purposes, three healthy, 3-year-old does with similar weights and distinct coat colors-white, black, and light brown-were selected. Methods: Skin samples were collected for transcriptome sequencing, and bioinformatics methods were applied to screen for differentially expressed genes (DEGs) in the skin of cashmere goats with varying coat colors. Real-time fluorescence quantitative PCR (qRT-PCR) and immunofluorescence were subsequently conducted to examine the expression patterns of these DEGs. Results: Th

SUBMITTER: Wu D 

PROVIDER: S-EPMC11855694 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature