Integrated Multi-Omics Analysis Reveals Glycosylation Involving 2-O-β-D-Glucopyranosyl-L-Ascorbic Acid Biosynthesis in <i>Lycium barbarum</i>.

ABSTRACT: L-ascorbic acid (vitamin C, AA) is widely present in plants, but humans lack the ability to synthesize it independently. As a potent reducing agent, AA is susceptible to oxidation, making the enhancement of its stability crucial. 2-O-β-D-glucopyranosyl-L-ascorbic acid (AA-2βG) is a stable natural derivative of AA with glycosylation, initially discovered in the fruits of Lycium barbarum. Understanding the biosynthesis of AA-2βG is crucial for enhancing its production in L. barbarum. While the established biosynthesis pathway of AA constitutes the upstream of AA-2βG biosynthesis, the conclusive step of β-glycosylation remains unclear. We identified a L. barbarum cultivar by UPLC, ZN01, with a high content of AA-2βG, and compared its leaves, immature fruits, and mature fr

SUBMITTER: Huang J 

PROVIDER: S-EPMC11855784 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature